Whooping cough (or, Pertussis) is an acute infectious,communicable disease affecting the respiratory tract, characterized by
spasmodic attacks of coughing & accompanied by an inspiratory whoop.
CAUSES
Causative organism – Haemophilus Pertussis (or Ordetella Pertussis)
- AGE- mostly less than 05 years.
- mostly females.
- Season -usually colder months.. Spread -by droplet infection
PATHOLOGY‣ The whole respiratory tract from nasopharynx down to bronchi is involved in a narcotizing inflammation along with inflammation of the peri-bronchial and tracheobronchial lymphoid tissue. The stickiness of exudate is responsible for obstruction of bronchioles leading to atelectasis.
SYMPTOMS
- Incubation period 01 to 03 weeks.
- CLINICALs Catarrhal stage: Duration – one week withgradual onset.
- Dry cough, vomiting occasionally following a severe bout of cough.
- Anorexia and insomnia.
- Sneezing, coryza and lacrymation (sometimes conjunctivitis).
- Moderate fevers.
- Paroxysmal Stage: Duration – 2 to 4 weeks.
- Cough(paroxysmal) 30 to 50 times a day. thick mucoid sputum and vomiting maybccur at the end of bouts.
- ‘Glottis may have ulcer, spasm and oedema.
- Tetany due to severe vomiting.
- Bleeding tendency i.e. haemoptysis, epistaxis, purpura,Whoop immediately following the intestinal haemorrhage may occur.
- Convalescent Stage: Usually begins within 4 weeks after the acute onset.
- Cough becomes less frequent and sputum is less tenacious.
- Vomiting may rarely occur as a matter of habit.
- Improving appetite.
- Immunity after illness lasts long.
INVESTIGATION
- CBC
- ESR
- SPUTUM CULTURE
- X-Ray Chest
PROGNOSIS
Better in older children and in the aged but comparatively worse below 03 years.
PROPHYLAXIS
Triple antigen should be given in a dose of 1-cc subcutaneously after every month for three doses. Booster doses after one year and once again before going to school.
COMPLICATIONS
- Pneumonia
- Emphysema
- Dyspnea
- Toxic Encephalitis
- Pneumothorax
- Umbilical hernia
- Convulsions
- Meningitis
- Cerebral hemorrhage
- Enteritis
- Otitis media
- Fulminant Tuberculosis
MANAGEMENT & TREATMENT
- Bed rest in a well ventilated calm and quiet room during catarrhal stage and for a time during paroxysmal stage.
- Diet liquids and semi solid diet, feeds should be given immediately after vomiting or paroxysms and should be small & frequent.
- Cough suppressants may also be used, e.g. phensedyl (promethazinecodeine, ephedrine) .
- Sedativeday Satriclofos (Tricloryl) syrup 250-mg.
- Antibiotics tetracycline 50-mg- per kg of body weight daily in divided doses (or Ampicillin 150-mgm. per kg of body wenght.Erythromycin 50-mg. or Hyper-immune convalescent serum 20-ml. intravenously at 2-3 days intervals.